Say no to Viagra

Say NO to insulin

H. pylori mobilizes cells elicobacter pylori infects the gastric track of more than half of the human population and is associated with an increased occurrence of invasive gastric cancers. On page 249, Churin et al. explain how this widespread bug turns tumors metastatic by corrupting a growth factor receptor. H H. pylori infection mobilizes gastric epithelial cells (right) by activating c-Met....

Say NO to hypoperfusion!

AUTOREGULATION is defined as the capacity of an organ or tissue to maintain a constant blood flow in the face of a change in perfusion pressure, while metabolism is unchanged. Under normal physiological conditions, large proximal arteries contribute little to the total resistance of a particular vascular bed. However, when atherosclerosis causes a conductance artery to narrow so that over 70% o...

Codeine: Time to Say "No".

Codeine has been prescribed to pediatric patients for many decades as both an analgesic and an antitussive agent. Codeine is a prodrug with little inherent pharmacologic activity and must be metabolized in the liver into morphine, which is responsible for codeine's analgesic effects. However, there is substantial genetic variability in the activity of the responsible hepatic enzyme, CYP2D6, and...

Why families say no to organ donation.

Why say no to tobacco: Indian perspective.

The burden of tobacco Tobacco (smoking or smokeless) use is one of the biggest public health threats the world has ever faced and it is one of the major preventable causes of death and disability worldwide. 1 Cigarette smoking is the most popular form of tobacco use. There are 1.1billion tobacco users in the world, 70% of whom are in low-income countries 2 . Tobacco use in children and adolesce...